| 18.04.2021 13:00 | Novi Pazar | 1 : 3 | Čukarički | |
| 18.04.2021 19:00 | TSC | 4 : 1 | Voždovac | |
| 18.04.2021 19:00 | Proleter | 0 : 1 | Mladost (L) | |
| 18.04.2021 19:00 | Spartak ŽK | 0 : 2 | Napredak | |
| 18.04.2021 19:00 | Radnički (N) | 0 : 0 | Javor Matis | |
| 18.04.2021 13:00 | Metalac | 0 : 0 | Inđija | |
| 18.04.2021 13:00 | Zlatibor | 1 : 2 | Rad |
| 18.04.2021 16:00 | Dinamo | 2 : 0 | OFK Žarkovo | |
| 18.04.2021 16:00 | RFK Grafičar | 4 : 1 | Trayal | |
| 18.04.2021 16:00 | Radnički (SM) | 2 : 1 | Budućnost | |
| 18.04.2021 16:00 | GFK Dubočica | 2 : 1 | Železničar (P) |
| 18.04.2021 17:00 | Radnik | 1 : 1 | Željezničar | |
| 18.04.2021 15:00 | Olimpik | 0 : 3 | Zrinjski | |
| 18.04.2021 19:00 | Široki Brijeg | 0 : 2 | Velež |
| 18.04.2021 16:30 | Tisa | 0 : 1 | Bačka 1901 | |
| 18.04.2021 16:30 | Borac | 3 : 1 | Dunav |
| 18.04.2021 16:00 | Jošanica | 2 : 1 | Mladi radnik 1926 | |
| 18.04.2021 16:00 | Budućnost (A) | 3 : 2 | Budućnost Krušik 2014 | |
| 18.04.2021 16:00 | Železničar (L) | 0 : 0 | Takovo |
| 18.04.2021 16:00 | Crvena zvezda | 1 : 0 | Radnički (O) | |
| 18.04.2021 16:00 | BSK 1925 | 0 : 1 | BASK | |
| 18.04.2021 16:00 | Sremčica | 3 : 2 | OFK Beograd | |
| 18.04.2021 16:00 | Leštane | 5 : 2 | BSK Borča | |
| 18.04.2021 17:30 | Studentski grad | 2 : 1 | TEK Sloga | |
| 18.04.2021 16:00 | Jedinstvo | 2 : 1 | Brodarac |
| 18.04.2021 16:30 | Mladost | 1 : 3 | Vlasina | |
| 18.04.2021 16:30 | Kablovi | 1 : 7 | Radan | |
| 18.04.2021 11:00 | Radnički (S) | 2 : 1 | OFK Topličanin | |
| 18.04.2021 11:00 | SFS Borac | 2 : 2 | Budućnost (P) |
| 18.04.2021 16:00 | Real | 0 : 3 | Šumadija 1903 | |
| 18.04.2021 16:00 | Radnik | 0 : 1 | Goč | |
| 18.04.2021 16:00 | Vodojaža | 3 : 2 | Mokra Gora | |
| 18.04.2021 16:00 | OFK Ras | 2 : 1 | Budućnost | |
| 18.04.2021 16:00 | Šumadija (T) | 3 : 0 | Novi Pazar 1928 |
| 18.04.2021 16:00 | OFK Napredak | 2 : 1 | Pomoravlje | |
| 18.04.2021 16:00 | Sloboda | 1 : 0 | Jasenica 2017 | |
| 18.04.2021 16:00 | Borac 1932 | 3 : 1 | OFK Aranđelovac 1979 | |
| 18.04.2021 16:00 | OFK Mihajlovac | 5 : 1 | Rudar (S) | |
| 18.04.2021 16:00 | Borac (Ž) | 1 : 2 | Sloga (M) |
| 18.04.2021 16:00 | Jasen | 1 : 1 | Jedinstvo Putevi | |
| 18.04.2021 16:00 | Rampa | 0 : 2 | Sloboda (Č) | |
| 18.04.2021 16:00 | Polet (T) | 4 : 0 | Sevojno | |
| 18.04.2021 16:00 | Prijevor | 1 : 0 | Parmenac | |
| 18.04.2021 16:00 | Zlatar | 5 : 0 | Polimlje |
| 18.04.2021 16:00 | Mladost (Dr) | 0 : 1 | Rubribreza | |
| 18.04.2021 16:00 | Borac (L) | 0 : 1 | Sloga (B) | |
| 18.04.2021 16:00 | Zadrugar | 2 : 3 | Mladost (P) | |
| 18.04.2021 16:00 | Radnički (K) | 0 : 0 | Ribnica | |
| 18.04.2021 16:00 | OFK Divci | 0 : 1 | Rađevac |
| 18.04.2021 16:30 | Hercegovac | 5 : 0 | Obilić | |
| 18.04.2021 16:30 | Bačka (P) | 1 : 1 | Bajša | |
| 18.04.2021 16:30 | Mladost (T) | 3 : 2 | OFK Vrbas | |
| 18.04.2021 16:30 | Mladost (BP) | 1 : 0 | Vojvodina (BG) | |
| 18.04.2021 16:30 | Tavankut | 3 : 1 | ČSK Pivara |
| 18.04.2021 16:30 | Radnički (K) | 3 : 0 | Proleter | |
| 18.04.2021 16:30 | ŽAK | 1 : 1 | Jedinstvo (BK) | |
| 18.04.2021 16:30 | Crvena zvezda | 4 : 2 | Budućnost | |
| 18.04.2021 16:30 | Banat | 0 : 1 | Borac |
| 18.04.2021 16:30 | Jedinstvo | 1 : 1 | Podunavac | |
| 18.04.2021 16:30 | Borac | 2 : 0 | Sloga (E) | |
| 18.04.2021 16:30 | Hajduk | 1 : 0 | Podrinje | |
| 18.04.2021 16:30 | Budućnost | 2 : 1 | Mladost | |
| 18.04.2021 16:30 | Jadran | 2 : 3 | Cement |
| 18.04.2021 16:30 | Temnić 1924 | 1 : 2 | Kopaonik | |
| 18.04.2021 16:30 | Bošnjane | 1 : 0 | Jedinstvo (M) | |
| 18.04.2021 16:30 | Moravac 2015 | 1 : 1 | Kušiljevo | |
| 18.04.2021 16:30 | OFK Lugomir | 1 : 2 | Juhor |
| 18.04.2021 16:30 | Hajduk Veljko | 9 : 0 | Lužnica | |
| 18.04.2021 16:30 | Rajko Mitić | 0 : 1 | Balkanski | |
| 18.04.2021 16:30 | Tanasko Rajić | 2 : 1 | OFK Knjaz |
| 18.04.2021 16:30 | Pukovac | 1 : 0 | Naša krila 1936 | |
| 18.04.2021 16:30 | Rudar | 4 : 0 | Naisus 1977 | |
| 18.04.2021 16:30 | Jedinstvo (GM) | 3 : 2 | Malošište | |
| 18.04.2021 16:30 | Orljane | 1 : 1 | OFK Brzi Brod | |
| 18.04.2021 16:30 | Zemljoradnik | 1 : 3 | Morava |
| 18.04.2021 16:30 | Alakince | 0 : 2 | Sloga | |
| 18.04.2021 16:30 | Vranjska Banja | 0 : 0 | Čekmin | |
| 18.04.2021 16:30 | Jedinstvo (GS) | 4 : 3 | Jablanica | |
| 18.04.2021 16:30 | Dobrič | 1 : 2 | Svetlost |
| 18.04.2021 16:00 | Kosmaj | 1 : 1 | Komgrap | |
| 18.04.2021 16:00 | Poštar Zvezdara | 3 : 1 | Torlak | |
| 18.04.2021 16:00 | Srem | 0 : 3 | BSK 1926 | |
| 18.04.2021 16:00 | Vrčin | 5 : 1 | Budućnost (Z) |
| 18.04.2021 16:30 | Rudar (P) | 2 : 1 | Midžor | |
| 18.04.2021 16:30 | Šljivar | 0 : 3 | OFK Rtanj | |
| 18.04.2021 16:30 | Kosovo | 1 : 1 | Graničar | |
| 18.04.2021 16:30 | Sloga | 1 : 1 | Trebič | |
| 18.04.2021 16:30 | Osnić | 2 : 7 | Ozren |
| 18.04.2021 16:30 | Vinogradar | 3 : 0 | Mačkovac | |
| 18.04.2021 16:30 | Mladost (DK) | 1 : 3 | Čitluk | |
| 18.04.2021 16:30 | 13. April | 3 : 1 | Sloga (D) | |
| 18.04.2021 16:30 | Mladost (T) | 2 : 1 | Sloga (L) | |
| 18.04.2021 16:30 | Žabare | 4 : 1 | Sloga (Ć) | |
| 18.04.2021 16:30 | Sebečevac | 4 : 1 | Donji Kopaonik | |
| 18.04.2021 16:30 | Ribnik | 0 : 8 | Kupci | |
| 18.04.2021 16:30 | FUD | 0 : 0 | Trudbenik |
| 18.04.2021 16:30 | PSK | 0 : 8 | Sremac | |
| 18.04.2021 16:30 | Borac (M) | 3 : 1 | Mitros | |
| 18.04.2021 16:30 | Hajduk (V) | 0 : 0 | GFK Sloven | |
| 18.04.2021 16:30 | Ljukovo | 2 : 1 | Rudar | |
| 18.04.2021 16:30 | Borac (K) | 1 : 5 | Donji Srem 2015 | |
| 18.04.2021 16:30 | LSK | 2 : 1 | BSK |
| 18.04.2021 16:30 | Jugoslavija | 2 : 5 | Strela | |
| 18.04.2021 16:30 | Radnički (B) | 1 : 3 | Dolina | |
| 18.04.2021 16:30 | Crvena zvezda | 1 : 1 | Budućnost (A) | |
| 18.04.2021 16:30 | Hajdučica | 1 : 4 | BAK | |
| 18.04.2021 16:30 | Banat (I) | 0 : 0 | Sloga (BNS) | |
| 18.04.2021 16:30 | Spartak 1911 | 2 : 2 | Potporanj | |
| 18.04.2021 16:30 | Partizan (G) | 1 : 2 | Polet (Id) |
| 18.04.2021 16:30 | Rusin | 0 : 0 | Borac 46 | |
| 18.04.2021 16:30 | Omladinac | 2 : 0 | Kordun | |
| 18.04.2021 16:30 | Maglić | 1 : 2 | Zadrugar | |
| 18.04.2021 16:30 | Kulpin | 0 : 2 | SU Stanišić 1920 | |
| 18.04.2021 16:30 | Slavija | 0 : 4 | Radnički 1918 | |
| 18.04.2021 16:30 | Budućnost (M) | 0 : 1 | Tvrđava |
| 18.04.2021 17:00 | Đurđin | 3 : 0 | Radnički 1905 | |
| 18.04.2021 17:00 | Sutjeska | 3 : 2 | Proleter (RS) | |
| 18.04.2021 17:00 | Iskra | 3 : 1 | Tornjoš | |
| 18.04.2021 17:00 | Proleter (Nj) | 2 : 1 | Preporod | |
| 18.04.2021 17:00 | Eđšeg | 0 : 3 | Napredak |
| 18.04.2021 16:30 | MSK | 6 : 0 | Lehel | |
| 18.04.2021 16:30 | Crvena zvezda | 2 : 0 | Rusanda | |
| 18.04.2021 16:30 | Potisje | 3 : 1 | Delija | |
| 18.04.2021 16:30 | Vojvodina (B) | 3 : 0 | Mladost (BD) | |
| 18.04.2021 16:30 | Radnički 1911 | 1 : 1 | Vojvodina (NM) | |
| 18.04.2021 16:30 | Polet | 2 : 0 | Tamiš |
| 18.04.2021 16:00 | Sloga (L) | 3 : 2 | Polet | |
| 18.04.2021 16:00 | Crvena zvezda | 0 : 1 | Mladi radnik 1940 | |
| 18.04.2021 16:00 | Podunavac | 4 : 0 | Bačinac | |
| 18.04.2021 16:00 | Sloga (M) | 0 : 3 | Osipaonica | |
| 18.04.2021 16:00 | Pobeda | 2 : 3 | Železničar Kusadak | |
| 18.04.2021 16:00 | Budućnost | 3 : 0 | SASK | |
| 18.04.2021 16:00 | Obilić | 0 : 1 | Radnik (SP) |
| 18.04.2021 16:00 | Plaskovac | 4 : 0 | Prvi srpski ustanak | |
| 18.04.2021 16:00 | ŽSK | 3 : 0 | Marjan (K) | |
| 18.04.2021 16:00 | Omladinac | 3 : 2 | Lokomotiva | |
| 18.04.2021 16:00 | Trnava | 4 : 0 | Sloga (Z) | |
| 18.04.2021 16:00 | Jasenica (B) | 3 : 0 | Šumadinac (S) | |
| 18.04.2021 16:00 | Banja 1957 | 3 : 1 | Partizan (BB) | |
| 18.04.2021 16:00 | BSK | 2 : 1 | Grizli ML | |
| 18.04.2021 16:00 | Šumadinac 1913 | 5 : 0 | Partizan 1945 |
| 18.04.2021 16:00 | Sinđelić 2012 | 0 : 3 | PKB (PS) | |
| 18.04.2021 11:00 | Hajduk | 3 : 6 | Borac (O) | |
| 18.04.2021 16:00 | Institut | 1 : 0 | Rakovica | |
| 18.04.2021 16:00 | Postar 1930 | 1 : 0 | DIF | |
| 18.04.2021 16:00 | Borac (P) | 0 : 3 | Balkan Mirijevo | |
| 18.04.2021 16:00 | Šumadinac | 2 : 2 | Posavac Tišma | |
| 18.04.2021 16:00 | PKB Kovilovo | 0 : 3 | Umka |
| 18.04.2021 16:00 | Rojkovac | 4 : 1 | Duboko | |
| 18.04.2021 16:00 | Polet | 0 : 5 | Mladost | |
| 18.04.2021 10:00 | Radnički | 2 : 2 | Barajevo | |
| 18.04.2021 16:00 | Vranić | 2 : 3 | OFK Budućnost | |
| 18.04.2021 16:00 | Strelac | 3 : 2 | OFK Zabrežje | |
| 18.04.2021 16:00 | Omladinac | 2 : 1 | OFK Borac | |
| 18.04.2021 16:00 | Jedinstvo | 0 : 4 | Zvezda |
| 18.04.2021 16:00 | Zuce 2019 | 3 : 1 | Dunavac | |
| 18.04.2021 16:00 | Ivanča | 3 : 5 | Šumadija 1962 | |
| 18.04.2021 16:00 | Rabrovac | 1 : 2 | SUF Kovačevac 1956 | |
| 18.04.2021 10:00 | Kaluđerica 1969 | 4 : 1 | Boleč | |
| 18.04.2021 16:00 | Velika Krsna | 3 : 0 | Kosmajac | |
| 18.04.2021 16:00 | Pudarci | 1 : 1 | Zaklopača |
| 18.04.2021 17:00 | Titel | 0 : 1 | Slavija | |
| 18.04.2021 17:00 | Šajkaš 1908 | 2 : 5 | Fruškogorac | |
| 18.04.2021 17:00 | TSK | 4 : 1 | ŽSK | |
| 18.04.2021 17:00 | Susek | 3 : 2 | Fruškogorski partizan | |
| 18.04.2021 17:00 | Jedinstvo | 3 : 1 | Petrovaradin | |
| 18.04.2021 17:00 | Hajduk | 2 : 2 | Bačka 1923 | |
| 18.04.2021 17:00 | Bačka (B) | 0 : 1 | OFK Futog | |
| 18.04.2021 17:00 | Tatra | 4 : 1 | Omladinac |
| 18.04.2021 16:30 | Mladost | 3 : 5 | Poreč | |
| 18.04.2021 11:00 | Ključ | 0 : 3 | Blizna | |
| 18.04.2021 16:30 | Radnički | 1 : 1 | Polet | |
| 18.04.2021 16:30 | Urovica | 0 : 3 | Sloga |
| 18.04.2021 16:00 | Maršić | 5 : 0 | OFK Bagremar | |
| 18.04.2021 16:00 | 21. oktobar | 3 : 5 | Šumadija 1934 | |
| 18.04.2021 16:00 | Mladost (P) | 3 : 0 | Kolonija | |
| 18.04.2021 16:00 | Sloboda (G) | 2 : 0 | Kutlovo | |
| 18.04.2021 16:00 | Slavija | 2 : 1 | Jedinstvo | |
| 18.04.2021 16:00 | Srbija | 3 : 3 | Sloga (D) | |
| 18.04.2021 16:00 | Šumadinac KG | 1 : 1 | Zastava |
| 18.04.2021 16:30 | Mladost (L) | 3 : 2 | Palilulac | |
| 18.04.2021 16:30 | Aluminjum | 2 : 3 | Planinac 1933 | |
| 18.04.2021 16:30 | Čegar 2013 | 1 : 5 | Vulkan 1963 | |
| 18.04.2021 16:30 | Crvena zastava | 0 : 2 | Radnički 1936 | |
| 18.04.2021 16:30 | Čegar 1946 | 2 : 0 | Stevan Nešticki | |
| 18.04.2021 16:30 | Morava | 2 : 3 | Mladost (DK) | |
| 18.04.2021 16:30 | Omladinac | 1 : 0 | Sloboda |
| 18.04.2021 16:00 | Integral | 2 : 1 | Napredak 1936 | |
| 18.04.2021 16:00 | Mladost (B) | 1 : 1 | Vihor | |
| 18.04.2021 16:00 | Rudar (Kr) | 3 : 1 | Manastirica | |
| 18.04.2021 16:00 | Borac (K) | 2 : 2 | Budućnost (V) | |
| 18.04.2021 16:00 | Mlava (ML) | 2 : 3 | Železničar | |
| 18.04.2021 16:00 | Sirakovo | 0 : 4 | Omladinac (Š) | |
| 18.04.2021 16:00 | Sloga (L) | 4 : 3 | Napredak Simićevo | |
| 18.04.2021 16:00 | Obilić | 2 : 1 | Rudar 2001 |
| 18.04.2021 16:30 | Mladost | 7 : 0 | Moravac (Č) | |
| 18.04.2021 16:30 | Baličevac | 2 : 1 | Radnički 1947 | |
| 18.04.2021 16:30 | OFK Rutevac 1908 | 1 : 3 | Palilula | |
| 18.04.2021 16:30 | Moravac (ZT) | 4 : 3 | Sloga | |
| 18.04.2021 16:30 | Elid | 2 : 2 | Rasovača | |
| 18.04.2021 16:30 | Pobeda | 1 : 1 | Jastrebac |
| 18.04.2021 16:30 | Mataruge | 0 : 0 | Karađorđe | |
| 18.04.2021 16:30 | Popovići Vrnjci | 1 : 4 | Mladi radnik 1925 | |
| 18.04.2021 16:30 | Tavnik | 3 : 0 | Granit | |
| 18.04.2021 16:30 | Jedinstvo 2017 | 4 : 0 | Jovo Kursula | |
| 18.04.2021 16:30 | Napredak | 2 : 3 | Rudar | |
| 18.04.2021 16:30 | Kraljevo Hajduk | 0 : 2 | Budućnost | |
| 18.04.2021 16:30 | Ribnica | 0 : 1 | Mladost (V) | |
| 18.04.2021 16:30 | Ibar | 3 : 0 | Gruža |
| 18.04.2021 16:00 | Juhor (G) | 2 : 2 | Rudar | |
| 18.04.2021 16:00 | Javor | 2 : 2 | Sloga | |
| 18.04.2021 16:00 | Budućnost (Đ) | 2 : 1 | Mladost (J) | |
| 18.04.2021 16:00 | Mladost (K) | 2 : 2 | Dragocvet | |
| 18.04.2021 16:00 | Resavac | 2 : 4 | OFK Juhor 2016 | |
| 18.04.2021 16:00 | Budućnost (M) | 4 : 0 | Napredak | |
| 18.04.2021 16:00 | Morava (R) | 1 : 2 | Morava (KS) | |
| 18.04.2021 16:00 | Partizan | 0 : 0 | Orlovi |
| 18.04.2021 16:00 | Pepeljevac | 0 : 1 | Dimitrije Tucović | |
| 18.04.2021 16:00 | OFK Senjak | 2 : 0 | Tvrdojevac | |
| 18.04.2021 16:00 | Kolubara 2 | 3 : 1 | Pambukovica | |
| 18.04.2021 16:00 | OFK Osečina | 1 : 2 | OFK Brđanac | |
| 18.04.2021 16:00 | Joks Junajted | 3 : 1 | Strmovo 1968 |
| 18.04.2021 16:30 | Vučje | 0 : 3 | Donja Lomnica | |
| 18.04.2021 16:30 | Progres | 2 : 1 | Polet | |
| 18.04.2021 16:30 | Gradac | 3 : 1 | OFK Brza | |
| 18.04.2021 16:30 | Zloćudovo | 2 : 2 | Umac | |
| 18.04.2021 16:30 | Kumarevo 65 | 1 : 7 | Bobište |
| 18.04.2021 16:30 | BSK | 5 : 1 | Mladi borac | |
| 18.04.2021 16:30 | Železničar | 2 : 4 | Mladost 1959 | |
| 18.04.2021 16:30 | Sloboda | 2 : 2 | Sloga | |
| 18.04.2021 16:30 | Milanovo | 3 : 0 | Moravac | |
| 18.04.2021 16:30 | Šumadija | 3 : 1 | Plantaža | |
| 18.04.2021 16:30 | OFK Morava | 1 : 2 | Real |
| 18.04.2021 16:00 | Jedinstvo | 7 : 3 | Prvi partizan | |
| 18.04.2021 16:00 | Polet | 1 : 1 | Savinac | |
| 18.04.2021 16:00 | Perućac | 1 : 3 | Višesava | |
| 18.04.2021 16:00 | Kotroman | 2 : 3 | Bakionica | |
| 18.04.2021 16:00 | Čajetina | 2 : 1 | Ježevica | |
| 18.04.2021 16:00 | Avijatičar Vranjani | 2 : 1 | Omladinac | |
| 18.04.2021 16:00 | Sečica | 1 : 4 | Lazarica |
| 18.04.2021 16:00 | Prilike | 1 : 4 | Slatina | |
| 18.04.2021 11:00 | Rakova | 0 : 4 | Jedinstvo | |
| 18.04.2021 16:00 | Voćar | 5 : 2 | Morava | |
| 18.04.2021 16:00 | Ozremica | 1 : 3 | Spartak |
| 18.04.2021 16:00 | Mladost (P) | 0 : 0 | Ozrem PMH | |
| 18.04.2021 16:00 | Zadrugar | 1 : 0 | Donja Vrbava | |
| 18.04.2021 16:00 | Napredak | 1 : 3 | Jedinstvo (K) | |
| 18.04.2021 16:00 | Rudar | 2 : 0 | Orlovac |
| 18.04.2021 16:00 | Gnjilan | 10 : 1 | Zadrugar | |
| 18.04.2021 16:00 | Mladost | 1 : 1 | Pobeda | |
| 18.04.2021 16:00 | Dragoš | 0 : 4 | Zvezda | |
| 18.04.2021 16:00 | Sloga | 0 : 4 | Napredak |
| 18.04.2021 16:30 | Karađorđe | 1 : 2 | Sinđelić | |
| 18.04.2021 16:30 | Sloga (LŠ) | 1 : 0 | Majur | |
| 18.04.2021 16:30 | Mladi borac | 2 : 0 | Duško | |
| 18.04.2021 16:30 | Cer (JL) | 0 : 3 | Drina | |
| 18.04.2021 11:00 | Vidojevica | 2 : 1 | Milan Orlić | |
| 18.04.2021 16:30 | Sloga (KR) | 2 : 3 | Mladost | |
| 18.04.2021 16:30 | Podrinje | 2 : 0 | Rudar | |
| 18.04.2021 16:30 | Jedinstvo | 3 : 1 | Hajduk Stanko |
| 18.04.2021 16:00 | Trnovac | 8 : 2 | Mineralac | |
| 18.04.2021 16:00 | Levosoje | 1 : 2 | Čelik | |
| 18.04.2021 16:00 | Lugina | 2 : 1 | BSK Bujanovac |
| 18.04.2021 16:00 | Gradac | 2 : 6 | Rubin | |
| 18.04.2021 16:00 | Beli Orlovi | 1 : 2 | Borac | |
| 18.04.2021 16:00 | Velika Drenova | 2 : 1 | Polet 57 | |
| 18.04.2021 16:00 | Omladinac (U) | 2 : 0 | Župski biseri |
| 18.04.2021 16:30 | Polet | 1 : 5 | Vulturul | |
| 18.04.2021 16:30 | Partizan (K) | 0 : 2 | Karaš (J) | |
| 18.04.2021 16:30 | Karaš (K) | 3 : 1 | Borac (VG) | |
| 18.04.2021 16:30 | Ševac | 1 : 0 | Omladinac | |
| 18.04.2021 16:30 | Graničar | 1 : 4 | Banat (D) | |
| 18.04.2021 16:30 | Borac (VS) | 3 : 1 | Ratar |
| 18.04.2021 16:30 | Borac (P) | 0 : 3 | Proleter | |
| 18.04.2021 16:30 | Mladost (V) | 0 : 1 | Omladinac (D) | |
| 18.04.2021 16:30 | Dolovo | 10 : 0 | Kolonija | |
| 18.04.2021 16:30 | BSK Bavanište | 2 : 1 | Budućnost (BB) |
| 18.04.2021 16:00 | ČSK | 4 : 1 | Graničar | |
| 18.04.2021 16:00 | Srem | 1 : 2 | Šumar | |
| 18.04.2021 16:00 | Jedinstvo | 1 : 0 | Hrtkovci | |
| 18.04.2021 16:00 | Krušedol | 1 : 1 | Radnički | |
| 18.04.2021 16:00 | Polet | 2 : 0 | Dunav | |
| 18.04.2021 16:00 | Fruškogorac | 2 : 2 | Mladost | |
| 18.04.2021 16:00 | Napredak | 0 : 1 | Sremac | |
| 18.04.2021 16:00 | OFK Brestač | 3 : 1 | Kameni |
| 18.04.2021 16:00 | Graničar 1924 | 2 : 1 | Sloga | |
| 18.04.2021 16:00 | Obilić 1993 | 6 : 0 | Sloboda | |
| 18.04.2021 16:00 | OFK Bikić | 1 : 0 | Trgovački | |
| 18.04.2021 16:00 | Erdevik 2017 | 2 : 1 | Fruška Gora | |
| 18.04.2021 16:00 | Jednota | 3 : 3 | Graničar (K) | |
| 18.04.2021 16:00 | Jedinstvo | 7 : 1 | Sremac (J) | |
| 18.04.2021 16:00 | OFK Zeka Buljubaša | 3 : 1 | Sremac (B) | |
| 18.04.2021 16:00 | Zmaj | 1 : 2 | Fruškogorac |
| 18.04.2021 16:30 | Zadrugar | 3 : 0 | Bilećanin | |
| 18.04.2021 16:30 | Tisa 1933 | 1 : 1 | Mladost | |
| 18.04.2021 16:30 | Naftagas | 2 : 2 | OFK Stajićevo | |
| 18.04.2021 16:30 | ŽFK Banat Bagljaš | 4 : 1 | Zlatica |
| 18.04.2021 16:00 | Mladost (R) | 1 : 3 | Radoje Domanović | |
| 18.04.2021 16:00 | Mladost (J) | 2 : 2 | Venčani | |
| 18.04.2021 16:00 | Budućnost | 1 : 6 | Mladi rudar | |
| 18.04.2021 11:00 | Gorski Car | 2 : 1 | Kopljari | |
| 18.04.2021 16:00 | Vrbica | 2 : 3 | Trešnjevica | |
| 18.04.2021 11:00 | B 2000 | 5 : 1 | Šamot |
| 18.04.2021 16:30 | Mladost | 4 : 2 | Aleksa Šantić | |
| 18.04.2021 16:30 | Jedinstvo | 0 : 4 | OFK Odžaci | |
| 18.04.2021 16:30 | Dinamo 1923 | 3 : 0 | Polet | |
| 18.04.2021 16:30 | Dunav | 0 : 6 | Bratstvo 2019 | |
| 18.04.2021 16:30 | Hajduk | 1 : 1 | Lipar | |
| 18.04.2021 16:30 | Omladinac | 2 : 2 | Terekveš |
| 18.04.2021 17:00 | Obilić | 0 : 1 | OFK Hajduk | |
| 18.04.2021 10:00 | Moskva | 1 : 2 | Slanobarac | |
| 18.04.2021 17:00 | Čenej | 6 : 0 | Sloga | |
| 18.04.2021 17:00 | Hajduk (G) | 1 : 2 | Borac (NS) | |
| 18.04.2021 17:00 | Vinogradar | 1 : 0 | Borac (R) | |
| 18.04.2021 17:00 | Dinamo | 2 : 0 | Miletić |
| 18.04.2021 16:00 | Dobrača | 1 : 2 | Jadran | |
| 18.04.2021 11:00 | Seljak | 1 : 3 | Bratstvo 1975 | |
| 18.04.2021 16:00 | Divostin | 1 : 3 | Košutnjak | |
| 18.04.2021 16:00 | Ćava | 2 : 0 | Partizan |
| 18.04.2021 16:00 | Ljubičevo | 3 : 2 | Polet (V) | |
| 18.04.2021 16:00 | Baštovan 2015 | 4 : 1 | Sloga (M) | |
| 18.04.2021 16:00 | Pek | 1 : 6 | Mlava (B) | |
| 18.04.2021 16:00 | Dizel | 1 : 1 | Napredak (B) | |
| 18.04.2021 16:00 | Batovac | 6 : 0 | Mladi Borac | |
| 18.04.2021 16:00 | Napredak (P) | 4 : 0 | Stig 1955 | |
| 18.04.2021 16:00 | Barič | 5 : 3 | BSK 1931 |
| 18.04.2021 16:00 | Zmaj 1953 | 1 : 2 | Velika Moštanica | |
| 18.04.2021 10:00 | Rekreativo 011 | 0 : 4 | Železnik 1930 | |
| 18.04.2021 16:00 | BUSK | 1 : 4 | Novi Beograd |
| 18.04.2021 16:00 | Sveti Stefan | 0 : 1 | Lepušnica | |
| 18.04.2021 11:00 | Mladi proleter | 0 : 3 | Pinosava | |
| 18.04.2021 16:00 | Boka Seniors | 4 : 5 | OFK Crvenka | |
| 18.04.2021 13:00 | Pionir | 2 : 1 | Palilulac |
| 18.04.2021 16:00 | Rušanj | 1 : 2 | OFK Boždarevac | |
| 18.04.2021 16:00 | Beljina | 3 : 1 | Veliki Borak |
| 18.04.2021 16:30 | Jedinstvo (G) | 2 : 1 | Mlada krila | |
| 18.04.2021 16:30 | Lazac | 1 : 2 | Progorelica | |
| 18.04.2021 16:30 | Zvezda | 2 : 0 | Jedinstvo (D) | |
| 18.04.2021 16:30 | Mladost 1925 | 0 : 0 | Mineral 2015 | |
| 18.04.2021 16:30 | Borac (V) | 1 : 1 | Miločajac | |
| 18.04.2021 16:30 | Braća Vuković | 5 : 1 | Borac (A) |
| 18.04.2021 16:00 | Zadrugar 1947 | 1 : 0 | Jedinstvo (K) | |
| 18.04.2021 16:00 | Borac (V) | 4 : 1 | Sloga 1945 | |
| 18.04.2021 16:00 | Krilaš | 4 : 1 | Radnički (K) | |
| 18.04.2021 16:00 | Mladost (R) | 1 : 1 | Polet S.D. | |
| 18.04.2021 16:00 | Pobeda 1953 | 4 : 1 | Bata Bulić |
| 18.04.2021 16:00 | OFK Batinac | 1 : 1 | Rudar (P) | |
| 18.04.2021 16:00 | Sloga | 2 : 1 | 15. Avgust 1950 | |
| 18.04.2021 16:00 | Radnički | 4 : 2 | Beljanica | |
| 18.04.2021 16:00 | Napredak (St) | 2 : 1 | Jasenovo |
| 18.04.2021 16:00 | Mladost (G) | 3 : 3 | GFK Tabane | |
| 18.04.2021 16:00 | Bratstvo | 1 : 0 | Kupinovac | |
| 18.04.2021 16:00 | Vinorača | 2 : 2 | Mladi Borac | |
| 18.04.2021 16:00 | Šantarovac | 3 : 0 | Mladost (D) | |
| 18.04.2021 16:00 | Ursule | 3 : 3 | Jedinstvo |
| 18.04.2021 17:00 | Ljubinić | 1 : 4 | Belo Polje | |
| 18.04.2021 17:00 | Rvati | 2 : 1 | Proleter | |
| 18.04.2021 17:00 | Sloga | 1 : 1 | Borac | |
| 18.04.2021 17:00 | Munja | 2 : 1 | OFK Urovci |
| 18.04.2021 16:00 | Joševa | 0 : 1 | OFK Paljuvi | |
| 18.04.2021 16:00 | Polet (DL) | 0 : 1 | Mladost (V) | |
| 18.04.2021 16:00 | Polet (T) | 2 : 2 | Ratkovac | |
| 18.04.2021 16:00 | Šarbane | 1 : 0 | Omladinac (K) | |
| 18.04.2021 16:00 | OFK Stublenica | 1 : 1 | Proleter (B) |
| 18.04.2021 16:30 | Omladinac | 2 : 0 | Napredak (BT) | |
| 18.04.2021 16:30 | Terekves | 1 : 2 | Napredak (Č) | |
| 18.04.2021 16:30 | Roham | 3 : 2 | Proleter |
| 18.04.2021 11:00 | Mladost (L) | 1 : 3 | Stari drugari | |
| 18.04.2021 11:00 | Žabari | 6 : 0 | Mali korak | |
| 18.04.2021 11:00 | Popadić | 0 : 0 | Toplica | |
| 18.04.2021 11:00 | Milenko Pavlović | 2 : 1 | Dračić 2018 | |
| 18.04.2021 11:00 | Polet | 2 : 0 | Komanice | |
| 18.04.2021 11:00 | Rakac Stave | 3 : 0 | Jadar 2013 |
| 18.04.2021 16:30 | Mladost (B) | 2 : 0 | Turekovac | |
| 18.04.2021 16:30 | Badince | 0 : 3 | Todorovce | |
| 18.04.2021 16:30 | Veliko Trnjane | 4 : 1 | Navalin | |
| 18.04.2021 16:30 | MB | 0 : 1 | Radnički | |
| 18.04.2021 16:30 | Mladost (DL) | 4 : 1 | Sušica 2012 |
| 18.04.2021 16:30 | Rujnik | 3 : 2 | Jasenovik 2018 | |
| 18.04.2021 16:30 | Sloga 1948 | 2 : 9 | Proleter | |
| 18.04.2021 16:30 | Mezgraja | 3 : 0 | Supovac |
| 18.04.2021 16:00 | Tempo | 1 : 2 | Borac | |
| 18.04.2021 11:00 | Polet (R) | 4 : 0 | Vukašinovac | |
| 18.04.2021 11:00 | OFK Sloga | 2 : 4 | Jedinstvo |
| 18.04.2021 16:30 | Tisa | 3 : 0 | Graničar | |
| 18.04.2021 16:30 | Šampion | 0 : 5 | Bačka | |
| 18.04.2021 16:30 | Jedinstvo | 8 : 0 | Tromedja | |
| 18.04.2021 16:30 | Jadran | 1 : 0 | Slavija | |
| 18.04.2021 16:30 | Hajduk | 2 : 3 | Potisje |
| 18.04.2021 16:00 | Kolarac | 6 : 0 | Vučak | |
| 18.04.2021 16:00 | Petrijevac | 2 : 3 | Lunjevac | |
| 18.04.2021 16:00 | Vožd 2020 | 3 : 0 | Landol |
| 18.04.2021 16:00 | Jezava | 2 : 1 | Zeppelin 026 | |
| 18.04.2021 16:00 | Godomin | 4 : 0 | OFK Slavija |
| 18.04.2021 17:00 | Mladost (Z) | 3 : 4 | Verko | |
| 18.04.2021 11:00 | Jedinstvo 2014 | 0 : 3 | Hajduk | |
| 18.04.2021 17:00 | Bobovik | 1 : 3 | Sloga 1949 | |
| 18.04.2021 17:00 | Sparta | 0 : 1 | Torpedo | |
| 18.04.2021 11:00 | Mladost 2013 | 0 : 1 | Polet | |
| 18.04.2021 11:00 | Belpos | 6 : 0 | Skupljen 2013 |
| 18.04.2021 16:30 | Jedinstvo | 1 : 1 | Mladost | |
| 18.04.2021 16:30 | Slemen | 9 : 0 | Sloga |
| 18.04.2021 16:30 | Glogonj | 5 : 0 | Tempo | |
| 18.04.2021 16:30 | Mundial | 3 : 4 | Pobeda | |
| 18.04.2021 16:30 | Omladinac 1927 | 1 : 7 | Jedinstvo Stević |
| 18.04.2021 16:00 | Gladijator | 1 : 6 | Čačak 94 | |
| 18.04.2021 16:00 | OFK Remont 1959 | 2 : 3 | Mršinci | |
| 18.04.2021 16:00 | Planinac | 0 : 3 | Malba | |
| 18.04.2021 16:00 | Gavrilo Princip | 0 : 2 | Budućnost | |
| 18.04.2021 11:00 | Prijatelji | 3 : 1 | Lugovi | |
| 18.04.2021 16:00 | Kej | 4 : 0 | Vujan |
| 18.04.2021 16:00 | Veliki Suvodol | 0 : 2 | Mladost |
| 18.04.2021 17:00 | Čantavir | 2 : 1 | OFK Mala Bosna 2015 | |
| 18.04.2021 17:00 | Solid | 0 : 0 | Udarnik Višnjevac | |
| 18.04.2021 17:00 | Lokomotiva | 7 : 3 | Palić | |
| 18.04.2021 17:00 | Elektrovojvodina | 2 : 1 | Bikovo |
| 18.04.2021 17:00 | Slavija | 0 : 8 | Orlovi (BP) | |
| 18.04.2021 17:00 | Proleter | 0 : 5 | Naša Zvezda | |
| 18.04.2021 17:00 | Neštin | 5 : 1 | Mladost (MB) | |
| 18.04.2021 17:00 | Bačka 1945 | 3 : 1 | Borac (V) | |
| 18.04.2021 17:00 | Bačka (D) | 7 : 0 | Krivanj |
| 18.04.2021 16:30 | Dobrava | 0 : 1 | Radnički | |
| 18.04.2021 16:30 | Vojvoda Stepa Stepanović | 1 : 2 | Mrovska | |
| 18.04.2021 16:30 | OFK Varna | 4 : 4 | Petrovac 74 | |
| 18.04.2021 16:30 | Vlašić | 4 : 3 | Šipurske livade | |
| 18.04.2021 16:30 | OFK Letnjikovac 1983 | 1 : 2 | Jevremovac | |
| 18.04.2021 16:30 | Trešnjevka | 4 : 3 | PSK | |
| 18.04.2021 16:30 | OFK Jelen | 3 : 2 | Pričinović |
| 18.04.2021 | Velereč 94 | 6 : 2 | FC Stella Rossa | |
| 18.04.2021 | Šumadija | 0 : 2 | Brezak | |
| 18.04.2021 | Majdan | 1 : 2 | Semedraž | |
| 18.04.2021 | Takovski Ustanak | 2 : 0 | Omladinac |
| 18.04.2021 16:30 | Antimon | 0 : 2 | Velika Reka | |
| 18.04.2021 16:30 | Borac | 0 : 1 | TE Gučevo | |
| 18.04.2021 16:30 | Sloga | 1 : 1 | Mladost | |
| 18.04.2021 16:30 | Jedinstvo (MZ) | 4 : 1 | 7. Juli | |
| 18.04.2021 16:30 | Jedinstvo (ZA) | 1 : 1 | Jadar 1961 |
| 18.04.2021 16:30 | Egeta | 4 : 1 | Omladinac | |
| 18.04.2021 16:30 | Koča Anđelković | 3 : 1 | Pontes | |
| 18.04.2021 16:30 | Kladušnica | : | Rtkovo | |
| 18.04.2021 16:30 | Mala Vrbica | 2 : 0 | Lokomotiva |
| 18.04.2021 16:00 | Jelica | 5 : 2 | Sloga | |
| 18.04.2021 16:00 | Vrelo | 2 : 1 | Gradina | |
| 18.04.2021 16:00 | Radnički | 3 : 3 | Gorušica | |
| 18.04.2021 16:00 | Bjelica | 1 : 2 | Brezova |
| 18.04.2021 16:00 | Budućnost (ZM) | 4 : 0 | Torpedo 1924 | |
| 18.04.2021 16:00 | Partizan | 1 : 4 | Omladinac (BO) | |
| 18.04.2021 16:00 | Sloboda | 3 : 0 | Napredak | |
| 18.04.2021 16:00 | Gorki | 4 : 1 | Petlovača |
| 18.04.2021 13:00 | Knjaz | 1 : 0 | Dobrinjac | |
| 18.04.2021 13:00 | Trešnjica | 7 : 3 | Glumač | |
| 18.04.2021 16:00 | Gorobilje | 0 : 0 | Duškovci | |
| 18.04.2021 16:00 | Napredak | 1 : 1 | Plavi Tok |
| 18.04.2021 16:30 | Mladost (R) | 2 : 2 | Pobeda | |
| 18.04.2021 16:30 | Mladost Radost | 6 : 0 | Sloboda | |
| 18.04.2021 16:30 | Slavija | 1 : 3 | Tomislavci |
| 18.04.2021 16:00 | Budućnost 1948 | 1 : 0 | Beli Orlovi | |
| 18.04.2021 16:00 | Šumadija | 4 : 1 | Udarnik |
| 18.04.2021 16:00 | Karadjordje | 0 : 5 | Omladinac | |
| 18.04.2021 16:00 | Jedinstvo | 4 : 2 | Mladost |
| 18.04.2021 11:00 | Balajnac | 0 : 4 | Dobrič 1974 | |
| 18.04.2021 11:00 | Rad 1974 | 4 : 0 | Jastrebac 1979 | |
| 18.04.2021 11:00 | Arbanasce | 6 : 0 | Lepaja 2018 |
| 18.04.2021 11:00 | Naupare | 2 : 2 | Gaglovo | |
| 18.04.2021 16:30 | Makrešane | 4 : 0 | Konjuh | |
| 18.04.2021 11:00 | Parunovac | 3 : 0 | Bukovica | |
| 18.04.2021 11:00 | Modrica | 3 : 0 | Zmajevac | |
| 18.04.2021 16:30 | Mudrakovac | 2 : 3 | Borac |
| 18.04.2021 11:00 | Toplica | 2 : 0 | Marina Kutina | |
| 18.04.2021 11:00 | 10. februar | 0 : 2 | Zaplanjac |
| 18.04.2021 16:00 | Umčari | 4 : 1 | Gročanski fudbalski klub | |
| 18.04.2021 16:00 | OFK Mladost | 0 : 1 | Podunavac |
| 18.04.2021 16:30 | Parcane | 3 : 3 | Obilić | |
| 18.04.2021 16:30 | Borjak 2012 | 5 : 2 | Mladost | |
| 18.04.2021 16:30 | Mladi radnik | 2 : 4 | Stara Čaršija |
| 18.04.2021 16:30 | Borac | 0 : 2 | Partizan | |
| 18.04.2021 16:30 | Proleter | 1 : 0 | KSK Konak 1926 |
| 18.04.2021 11:00 | Studen Vitez | 5 : 1 | Šumadija | |
| 18.04.2021 16:30 | Partizan | 4 : 1 | Stara Čaršija | |
| 18.04.2021 11:00 | Omladinac | 4 : 0 | BSK 2014 | |
| 18.04.2021 16:30 | Budućnost | 0 : 2 | Magnohrom |
| 18.04.2021 16:00 | Donji Petrovci | 4 : 3 | Vojvodina | |
| 18.04.2021 16:00 | Borac (J) | 3 : 2 | 27. Oktobar | |
| 18.04.2021 16:00 | Fruškogorac | 2 : 1 | Sloga (K) | |
| 18.04.2021 16:00 | Graničar | 4 : 2 | Polet | |
| 18.04.2021 16:00 | Borac (S) | 1 : 3 | Car Uroš | |
| 18.04.2021 16:00 | Sloga (S) | 0 : 2 | Jedinstvo (K) |
| 18.04.2021 11:00 | Sovljak | 3 : 0 | Murgaš 2012 | |
| 18.04.2021 11:00 | Gunjevac | 3 : 3 | Budućnost 1995 | |
| 18.04.2021 11:00 | Jedinstvo (M) | 6 : 1 | Tamnava | |
| 18.04.2021 11:00 | Vrelo | 3 : 1 | Sloga (V) | |
| 18.04.2021 11:00 | OFK Takovo | 1 : 0 | Vukona |
| 18.04.2021 16:00 | Donja Mutnica | 0 : 2 | Omladinac | |
| 18.04.2021 16:00 | ISK Izvor | 3 : 1 | Popovac |
| 18.04.2021 16:00 | Potočac | 3 : 1 | Istok 63 | |
| 18.04.2021 16:00 | Razvitak | 4 : 1 | Hajduk | |
| 18.04.2021 16:00 | Moravac | 1 : 1 | Heroj |
| 18.04.2021 16:30 | Graničar (R) | 3 : 0 | Jedinstvo Lemeš |
| 18.04.2021 17:00 | Omladinac | 2 : 0 | Oniks | |
| 18.04.2021 17:00 | Domaćin | 1 : 2 | Napredak | |
| 18.04.2021 17:00 | Mladost | 1 : 2 | OFK Dragoševac | |
| 18.04.2021 17:00 | Dražmirovac | 1 : 4 | Trnava |
| 18.04.2021 11:00 | Stig (MC) | 4 : 3 | Napredak 1927 |
| 18.04.2021 16:30 | Banatul | 3 : 2 | Naša Krajina |
| 18.04.2021 16:30 | Hajduk | 2 : 5 | Vinogradar | |
| 18.04.2021 16:30 | Vitorul | 1 : 1 | Pobeda |
| 18.04.2021 17:00 | OFK Radnički | 6 : 0 | Sloboda | |
| 18.04.2021 17:00 | Dimitrije Tucović | 4 : 1 | Proleter |
| 18.04.2021 17:00 | Mladost | 3 : 0 | Bistrica | |
| 18.04.2021 17:00 | Šumadinac | 2 : 1 | OFK Polet |
| 18.04.2021 11:00 | Maskar | 3 : 2 | Jarmenovci | |
| 18.04.2021 11:00 | Kalipolje | 4 : 1 | Budućnost MI |
| 18.04.2021 16:00 | Omladinac | 1 : 1 | Udarnik 2015 | |
| 18.04.2021 11:00 | Melnica | 1 : 6 | Dobrnje | |
| 18.04.2021 16:00 | BSK | 3 : 1 | Burovac |
| 18.04.2021 11:00 | Mladost | 4 : 1 | Radnik 2013 | |
| 18.04.2021 10:00 | Napredak | 0 : 1 | Rudar 1973 | |
| 18.04.2021 10:30 | Jašunja | 4 : 1 | Gornje Sinkovce |
| 18.04.2021 16:00 | Jovanovac | 2 : 4 | Hajduk 1936 | |
| 18.04.2021 16:00 | Stanovo 1941 | 1 : 0 | Bukorovac | |
| 18.04.2021 16:00 | Kremenac | 2 : 2 | Kragujevac |
| 18.04.2021 16:00 | Napredak 1934 | 1 : 2 | Beli Orao | |
| 18.04.2021 16:00 | Sloga (D) | 5 : 4 | Pobeda |
| 18.04.2021 16:00 | Moravac 1933 | 1 : 3 | Sopot | |
| 18.04.2021 16:00 | Sloga 1932 | 3 : 0 | Morava 1932 |
| 18.04.2021 16:30 | Borac (VR) | 1 : 1 | OFK Bosut | |
| 18.04.2021 16:30 | Sloga | 3 : 2 | Planinac | |
| 18.04.2021 16:30 | Srem (SR) | 1 : 1 | Srem (SM) | |
| 18.04.2021 16:30 | Borac (R) | 2 : 2 | Poletarac |
| 18.04.2021 11:00 | Rudar | 7 : 0 | Sava | |
| 18.04.2021 11:00 | Korman | 3 : 3 | Dobrava Žabar 2020 | |
| 18.04.2021 11:00 | Borac BTG | 4 : 2 | Miloš Pocerac | |
| 18.04.2021 11:00 | Mladost Svileuva | 2 : 2 | Galeb 1984 |
| 18.04.2021 11:00 | Metlić | 4 : 2 | Jedinstvo | |
| 18.04.2021 11:00 | Mladost | 1 : 1 | Zablaće |
| 18.04.2021 11:00 | Culjković | 2 : 3 | Roma - Odžino selo | |
| 18.04.2021 11:00 | POFK Letnjikovac | 0 : 3 | POFK Metaloplastika 2006 |
| 18.04.2021 16:00 | Jedinstvo | 2 : 0 | BSK | |
| 18.04.2021 16:00 | Mladost | 1 : 1 | Sloga | |
| 18.04.2021 16:00 | Proleter | 3 : 2 | Budućnost |
| 18.04.2021 16:30 | Granit | 0 : 1 | Luk Kompenzatori | |
| 18.04.2021 13:30 | Paskovac | 3 : 1 | Jadar | |
| 18.04.2021 16:30 | Sloga | 1 : 1 | Mladost (B) |
| 18.04.2021 16:00 | Mirko Tomić | 1 : 2 | Ram | |
| 18.04.2021 16:00 | Dunavac 1929 | 0 : 0 | Radnički (P) |
| 18.04.2021 16:00 | Napredak | 0 : 2 | Planinac | |
| 18.04.2021 16:00 | Resava | 2 : 5 | Mladi radnik |
| 18.04.2021 11:00 | Kruševica | 3 : 1 | Polet | |
| 18.04.2021 11:00 | Vratare | 0 : 3 | Dvorane | |
| 18.04.2021 16:30 | Mladost 2015 | 4 : 1 | Lomnica | |
| 18.04.2021 16:30 | Grkljane | 2 : 2 | Dedina |
| 18.04.2021 16:30 | OFK Bačinci | 3 : 0 | Graničar | |
| 18.04.2021 16:30 | Sinđelić | 2 : 2 | OFK Bingula | |
| 18.04.2021 16:30 | Omladinac | 4 : 3 | Borac |
| 18.04.2021 16:30 | Lovac | 2 : 1 | Kupinovo | |
| 18.04.2021 16:30 | Sloven | 8 : 2 | Vitez | |
| 18.04.2021 16:30 | Mladost 1935 | 0 : 5 | Hajduk 1932 |
| 18.04.2021 16:00 | Jedinstvo | 3 : 1 | Igalo | |
| 18.04.2021 16:00 | Arsenal | 1 : 0 | Ibar | |
| 18.04.2021 16:00 | Kom | 1 : 2 | Drezga | |
| 18.04.2021 16:00 | Grbalj | 1 : 2 | Mornar | |
| 18.04.2021 16:00 | Berane | 1 : 1 | Bokelj |
| 18.04.2021 14:30 | Arsenal | 1 : 1 | Fulham | |
| 18.04.2021 17:00 | Manchester United | 3 : 1 | Burnley |
| 18.04.2021 16:00 | Coventry City | 2 : 0 | Barnsley | |
| 18.04.2021 13:00 | Rotherham United | 0 : 1 | Birmingham City |
| 18.04.2021 16:15 | Deportivo Alavés | 1 : 0 | Huesca | |
| 18.04.2021 16:15 | Atletico Madrid | 5 : 0 | Eibar | |
| 18.04.2021 18:30 | Real Betis | 2 : 2 | Valencia | |
| 18.04.2021 21:00 | Getafe | 0 : 0 | Real Madrid | |
| 18.04.2021 18:30 | Cádiz | 0 : 0 | Celta Vigo | |
| 18.04.2021 21:00 | Levante | 1 : 5 | Villarreal | |
| 18.04.2021 14:00 | Osasuna | 2 : 0 | Elche | |
| 18.04.2021 14:00 | Real Sociedad | 1 : 2 | Sevilla |
| 18.04.2021 15:30 | Borussia Dortmund | 4 : 1 | Werder |
| 18.04.2021 17:05 | Bordeaux | 0 : 3 | Monaco | |
| 18.04.2021 15:00 | Brest | 1 : 1 | Lens | |
| 18.04.2021 15:00 | Dijon | 2 : 0 | Nice | |
| 18.04.2021 21:00 | Nantes | 1 : 2 | Olympique Lyonnais | |
| 18.04.2021 15:00 | Nîmes | 1 : 1 | Strasbourg | |
| 18.04.2021 13:00 | PSG | 3 : 2 | Saint-Etienne | |
| 18.04.2021 15:00 | Reims | 0 : 0 | Metz |
| 18.04.2021 15:00 | Lazio | 5 : 3 | Benevento | |
| 18.04.2021 12:30 | Milan | 2 : 1 | Genoa | |
| 18.04.2021 20:45 | Napoli | 1 : 1 | Internazionale | |
| 18.04.2021 15:00 | Atalanta | 1 : 0 | Juventus | |
| 18.04.2021 18:00 | Torino | 3 : 1 | Roma | |
| 18.04.2021 15:00 | Bologna | 4 : 1 | Spezia |
| 18.04.2021 13:00 | Moskva | 8 : 2 | Radnički 2012 | |
| 18.04.2021 16:00 | Heroj Polet | 1 : 5 | Napredak Junior 2018 | |
| 18.04.2021 16:30 | ŽGFK Lavice Dubočica | 1 : 2 | Jedinstvo 2014 |
| 18.04.2021 11:30 | Voša AS | 0 : 3 | Proleter |
| 18.04.2021 10:00 | Borac | 1 : 5 | Karađorđe | |
| 18.04.2021 11:00 | Kraljica Marija | 1 : 3 | Jedinstvo | |
| 18.04.2021 12:00 | Požega | 1 : 2 | Slatke male |
| 18.04.2021 14:00 | Rudar 1974 | 1 : 5 | Mašinac 2020 |
| 18.04.2021 16:30 | Radnički (NB) | 2 : 2 | Vojvodina | |
| 18.04.2021 11:00 | Radnički 1923 | 0 : 1 | Partizan | |
| 18.04.2021 10:00 | Čukarički | 4 : 1 | Brodarac | |
| 18.04.2021 13:00 | Crvena zvezda | 3 : 1 | Napredak | |
| 18.04.2021 13:00 | IMT | 2 : 0 | Trayal | |
| 18.04.2021 10:00 | Rad | 0 : 1 | Voždovac |
| 18.04.2021 10:00 | Radnički (SM) | 0 : 1 | Železničar | |
| 18.04.2021 10:00 | Index | 1 : 3 | Vojvodina | |
| 18.04.2021 10:00 | Radnički (NP) | 9 : 1 | Dinamo 1945 | |
| 18.04.2021 10:00 | Jedinstvo (V) | 1 : 5 | Inđija | |
| 18.04.2021 10:00 | Podrinje | 0 : 0 | Omladinac |
| 18.04.2021 10:00 | Spartak ŽK | 1 : 3 | Petrika | |
| 18.04.2021 10:00 | Radnički 1912 | 4 : 0 | Tisa Njerš | |
| 18.04.2021 10:00 | OFK Bačka | 4 : 1 | RFK Novi Sad 1921 | |
| 18.04.2021 10:00 | Bačka 1901 | 1 : 2 | Kabel |
| 18.04.2021 16:00 | Morava (VP) | 0 : 3 | GFK Sloboda | |
| 18.04.2021 11:00 | Metalac | 0 : 1 | Sloga (K) | |
| 18.04.2021 12:30 | Jedinstvo (Ub) | 2 : 1 | Borac 1926 | |
| 18.04.2021 16:00 | Radnički (V) | 1 : 0 | Šumadija 1903 | |
| 18.04.2021 13:00 | Javor Matis | 3 : 2 | Šabac Sunrise | |
| 18.04.2021 16:00 | Loznica | 2 : 2 | Sloga (P) |
| 18.04.2021 | Bor 1919 | 7 : 3 | OFK Topličanin | |
| 18.04.2021 | GFK Jagodina | 3 : 0 | Radnički (S) | |
| 18.04.2021 | Jedinstvo (P) | 2 : 1 | Trstenik PPT |
| 18.04.2021 12:00 | Sloga 33 | : | Jasenica 2017 |
| 18.04.2021 11:00 | Zvezda | 1 : 2 | Šumadija |
| 18.04.2021 11:00 | BSK Borča | 3 : 0 | 011 |
| 18.04.2021 10:00 | Siti Sport Klub | 1 : 0 | Leštane | |
| 18.04.2021 10:00 | Crvenka | 8 : 1 | Balkan |
| 18.04.2021 14:00 | Mladost | 11 : 0 | Korićani | |
| 18.04.2021 16:00 | Takovo | 2 : 1 | Radnički 1923 | |
| 18.04.2021 14:00 | Sušica | 0 : 1 | Jedinstvo Putevi |
| 18.04.2021 10:00 | Železničar | 5 : 0 | Spartak |
| 18.04.2021 | Vinogradar | 4 : 0 | Kevi |
| 18.04.2021 18:15 | Zemun | 0 : 1 | Partizan | |
| 18.04.2021 12:30 | Čukarički | 2 : 0 | Brodarac | |
| 18.04.2021 11:00 | Crvena zvezda | 1 : 2 | Napredak | |
| 18.04.2021 13:00 | Teleoptik | 1 : 1 | Real Niš | |
| 18.04.2021 12:30 | Rad | 3 : 1 | OFK Vršac |
| 18.04.2021 12:00 | Radnički (SM) | 4 : 2 | Železničar | |
| 18.04.2021 12:00 | Index | 2 : 6 | Vojvodina | |
| 18.04.2021 12:00 | Radnički (NP) | 1 : 1 | Dinamo 1945 | |
| 18.04.2021 12:00 | OFK Vršac | 2 : 5 | Inđija | |
| 18.04.2021 12:00 | Podrinje | 2 : 1 | Omladinac |
| 18.04.2021 12:00 | Spartak ŽK | 3 : 0 | Petrika | |
| 18.04.2021 12:00 | Radnički 1912 | 2 : 0 | Tisa Njerš | |
| 18.04.2021 12:00 | OFK Bačka | 0 : 3 | RFK Novi Sad 1921 |
| 18.04.2021 13:00 | Novi Pazar | 6 : 1 | Budućnost Krušik 2014 |
| 18.04.2021 | GFK Dubočica | 0 : 0 | Radnički (N) | |
| 18.04.2021 | Timočanin | 3 : 0 | Radnik | |
| 18.04.2021 | GFK Jagodina | 6 : 0 |